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Rimstar 4

Rimstar 4

Manufacturer:

Sandoz

Distributor:

Zuellig
Concise Prescribing Info
Contents
Rifampicin 150 mg, INH 75 mg, pyrazinamide 400 mg, ethambutol HCl 275 mg
Indications/Uses
Management of TB & certain opportunistic mycobacterial infections.
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Dosage/Direction for Use
Patient ≥71 kg 5 tab/day, 55-70 kg 4 tab/day, 38-54 kg 3 tab/day, 30-37 kg 2 tab/day.
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Overdosage
View Rimstar 4 overdosage for action to be taken in the event of an overdose.
Administration
Should be taken on an empty stomach: Take at least 30 min before meals. Swallow whole, do not chew/crush.
Contraindications
Hypersensitivity. History of drug-induced hepatitis, acute liver diseases, peripheral & optic neuritis.
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Warnings
For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Rimstar 4 detailed prescribing information
Special Precautions
Impaired renal, liver, visual function; diabetes mellitus, chronic alcoholism & undernourished patients. History of gout, convulsive disorders & acute porphyria. Pregnancy & lactation. Childn <8 yr. Elderly.
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Adverse Reactions
Hepatic, renal & hematologic effects. GI effects eg, nausea, abdominal pain, vomiting, pseudomembranous colitis, epigastric distress, anorexia. Central & peripheral nervous system effects eg, tiredness, drowsiness, headache, dizziness, ataxia, confusion, muscular weakness, visual disturbances, peripheral neuropathy. Skin & allergic effects eg, rash, fever, urticaria, pruritus. Rifampicin: Endocrine effects. Ethambutol: Acute gout (rare).
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Drug Interactions
OC or HRT, anticoagulants, antacids, cimetidine, morphine, codeine, disulfiram, anti-anxiety drugs, sulfinpyrazone, allopurinol, colchicine, probenecid, steroids, chloramphenicol, ketoconazole, dapsone, methadone, theophylline, cyclosporin A, azathioprine, diuretic & neurotoxic drugs.
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Storage
View Rimstar 4 storage conditions for details to ensure optimal shelf-life.
Description
View Rimstar 4 description for details of the chemical structure and excipients (inactive components).
Action
View Rimstar 4 mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Anti-TB Agents
ATC Classification
J04AM06 - rifampicin, pyrazinamide, ethambutol and isoniazid ; Belongs to the class of combination drugs used in the systemic treatment of tuberculosis.
Presentation/Packing
Form
Rimstar 4 film-coated tab
Packing/Price
60's (P661.85/pack)
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